Thermo Fisher Scientific Fbx32 Polyclonal Antibody, FITC
FITC로 표지된 Fbx32 폴리클로날 항체로, Western blot, IHC, ELISA, IP 등 다양한 응용에 적합합니다. Mouse와 Rat에 반응하며 Rabbit IgG 호스트로 제작되었습니다. 근육 위축 관련 단백질 연구에 유용한 연구용 시약입니다.
- 카탈로그번호
- ATR-FITC
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Fbx32 Polyclonal Antibody, FITC
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 240–280 on Atr1 protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the F-box protein family characterized by an approximately 40 amino acid motif, the F-box. F-box proteins are one of the subunits of the ubiquitin protein ligase complex SCFs, functioning in phosphorylation-dependent ubiquitination.
They are divided into three classes: Fbws (WD-40 domains), Fbls (leucine-rich repeats), and Fbxs (various interaction modules or no recognizable motifs).
The encoded protein belongs to the Fbxs class and contains an F-box domain. It is highly expressed during muscle atrophy, and mice deficient in this gene show resistance to atrophy. Therefore, this protein is a potential drug target for muscle atrophy treatment.
Alternative splicing results in two transcript variants encoding isoforms of different sizes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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