Thermo Fisher Scientific Fbx32 Polyclonal Antibody, Biotin
Fbx32 단백질을 인식하는 Thermo Fisher Scientific의 Biotin 결합 폴리클로날 항체. Western blot, IHC, ELISA, IP 등 다양한 응용 가능. 근육 위축 관련 연구에 유용하며, 토끼 유래 IgG 형태로 제공됨. 연구용 전용 제품.
- 카탈로그번호
- ATR-BIOTIN
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide taken within amino acid region 240–280 on Atr1 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the F-box protein family, characterized by an approximately 40 amino acid F-box motif. F-box proteins are part of the SCF ubiquitin ligase complex, involved in phosphorylation-dependent ubiquitination. They are classified into three groups:
- Fbws: contain WD-40 domains
- Fbls: contain leucine-rich repeats
- Fbxs: contain various interaction modules or no recognizable motifs
The encoded protein belongs to the Fbxs class and includes an F-box domain. It is highly expressed during muscle atrophy, and mice deficient in this gene show resistance to atrophy. Therefore, this protein is a potential drug target for muscle atrophy treatment. Alternative splicing results in two transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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