Thermo Fisher Scientific AMOT Polyclonal Antibody
Human AMOT 단백질을 인식하는 Rabbit Polyclonal Antibody로, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품.
- 카탈로그번호
- PA5111627
- 판매단위
- pk
카탈로그
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human AMOT. Recombinant protein control fragment (Product # RP-108533) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2857037 |
Product Specific Information
Immunogen sequence:
PFKGMPPQSV VCKPQEPGHF YSEHRLNQPG RTEGQLMRYQ HPPEYGAARP AQDISLPLSA RNSQ
Target Information
AMOT (Angiomotin) belongs to the motin family of angiostatin-binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs.
AMOT plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which regulates the uptake of polarity proteins at tight junctions.
AMOT is expressed predominantly in endothelial cells of capillaries and larger vessels of the placenta, where it may mediate the inhibitory effect of angiostatin on tube formation and endothelial cell migration during angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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