Thermo Fisher Scientific Synaptophysin Monoclonal Antibody (SYP02)
Synaptophysin 단백질을 타깃하는 단클론 항체로, 인간, 마우스, 랫트 시료에 반응합니다. Western blot, IHC, ICC 등 다양한 응용에 적합하며, 신경세포 말단 및 신경내분비 종양 마커로 활용됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:250 | - |
| Immunohistochemistry (IHC) | - | 6 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | - |
| Immunocytochemistry (ICC/IF) | - | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SYP02 |
| Immunogen | A synthetic peptide encoding a region near the C-terminal end of the synaptophysin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Tissue culture supernatant |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10982708 |
Product Specific Information
MA5-11575 targets Synaptophysin in IHC (P) applications and shows reactivity with Human and Rat samples.
The MA5-11575 immunogen is a synthetic peptide encoding a region near the C-terminal end of the synaptophysin protein.
Target Information
Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons.
It has four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting an involvement in synaptic vesicle endocytosis.
Synaptophysin is also involved in the regulation of short-term and long-term synaptic plasticity.
It is widely used as a marker for nerve terminals and for differentiating neuroendocrine tumors.
Mutations in the gene can result in X-linked mental retardation (MRX96).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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