Thermo Fisher Scientific MRPS5 Polyclonal Antibody
Rabbit polyclonal antibody against human MRPS5 protein. Validated for IHC (Paraffin) with 1:50–1:100 dilution. Detects endogenous MRPS5 levels. Purified via antigen affinity chromatography, supplied in PBS with 50% glycerol. For research use only.
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- PA550061
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Applications
Tested Applications and Dilution
- Immunohistochemistry (Paraffin) (IHC-P): 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human MRPS5 (aa 367–416) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635514 |
Product Specific Information
This antibody detects endogenous levels of total MRPS5 protein.
Target Information
Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both composed of multiple mitochondrial ribosomal proteins (MRPs) encoded by nuclear genes. These proteins are essential for mitochondrial protein synthesis.
MRP-S5 (mitochondrial ribosomal protein S5), also known as S5mt, is a 430-amino-acid mitochondrial protein belonging to the ribosomal protein S5P family. It is a component of the 28S subunit, contains one S5 DRBM domain, and exists as two alternatively spliced isoforms.
The gene encoding MRP-S5 is located on human chromosome 2, which spans approximately 237 million bases, includes over 1,400 genes, and represents about 8% of the human genome. Genetic disorders associated with chromosome 2 include Harlequin ichthyosis, sitosterolemia, and Alstrom syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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