Thermo Fisher Scientific MYOM1 Polyclonal Antibody
MYOM1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 사람 시료에 반응하며 IHC(P)에서 1:50~1:100 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용.
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Applications
Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human MYOM1 (aa 824–873, UniProt ID: P52179-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635516 |
Product Specific Information
This antibody detects endogenous levels of total MYOM1 protein.
Target Information
The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of titin extends into the M line, where it binds to M-band constituents such as myomesin 1 (190 kD) and myomesin 2 (165 kD).
Myomesin 1 and 2 contain structural modules homologous to fibronectin type III and immunoglobulin C2 domains. Both proteins share 50% sequence identity in their repeat-containing regions and contribute to the structural integrity of the sarcomere through muscle-specific immunoglobulin-like protein interactions.
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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