Thermo Fisher Scientific Phospho-WNK4 (Ser575) Polyclonal Antibody
WNK4 단백질의 Ser575 인산화 형태를 특이적으로 인식하는 폴리클로날 항체. Western blot 및 IHC(Paraffin) 실험에 적합. 사람, 마우스, 랫트 반응성. 고순도 정제 및 안정한 PBS/glycerol 저장용액 제공.
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Applications
Western Blot (WB)
Immunohistochemistry (Paraffin) (IHC (P))
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human WNK4 around the phosphorylation site of Ser575 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2899309 |
Product Specific Information
Antibody detects endogenous levels of WNK4 only when phosphorylated at Ser575.
Target Information
This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells and regulates the balance between NaCl reabsorption and K(+) secretion. It controls the activities of several ion channels, cotransporters, and exchangers involved in epithelial electrolyte flux. Mutations in this gene result in pseudohypoaldosteronism type IIB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-114673_WNK4_Q96J92-1_Rabbit.svg, PA5-114673_WNK4_Q96J92-1_Rabbit_PDP.jpeg)
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