Thermo Fisher Scientific PPT1 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human PPT1 protein. Validated for WB and IHC-P applications. High purity (>95%) and affinity-purified. Supplied as liquid, 1 mg/mL concentration, unconjugated. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
Product Specifications
| Item | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 50–100 of Human PPT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4 °C short term. For long-term storage, store at −20 °C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719088 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% (by SDS-PAGE).
Target Information
The PPT1 protein is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. It removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Mutations in this gene are associated with infantile neuronal ceroid lipofuscinosis 1 (CLN1, INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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