Thermo Fisher Scientific GABRB2 Polyclonal Antibody
GABRB2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간, 마우스, 랫트에 반응합니다. Western blot 및 IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 1 mg/mL 농도, 장기 보관 시 -20°C 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 400–450 of Human GABRB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719092 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. Purity is >95% (by SDS-PAGE).
Target Information
GAD-65 and GAD-67, glutamate decarboxylases, catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system, GABA acts as the main inhibitory neurotransmitter by increasing Cl⁻ conductance that inhibits neuronal firing.
GABA activates ionotropic (GABAA) and metabotropic (GABAB) receptors, as well as GABAC receptors.
Members of the GABAA receptor family include GABAA Rα1–6, GABAA Rβ1–3, GABAA Rγ1–3, GABAA Rδ, GABAA Rε, GABAA Rρ1, and GABAA Rρ2.
The GABAB family includes GABAB R1α and GABAB R1β.
GABA transporters (GABA T-1, T-2, T-3; also designated GAT-1, -2, -3) function to terminate GABA action.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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