Thermo Fisher Scientific Ankyrin 1 Monoclonal Antibody (N388A/10), PE
PE 형광으로 표지된 Ankyrin 1 단클론 항체로, 인간·마우스·랫트 시료에서 Ankyrin-R 검출에 적합. WB, IHC, ICC/IF 등 다양한 응용 가능. Protein G 정제, 1 mg/mL 농도, 4°C 보관. Ankyrin-B/G와 교차반응 없음.
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Applications
- Western Blot (WB): 1:1,000
- Immunohistochemistry (IHC): Assay-dependent
- Immunocytochemistry (ICC/IF): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N388A/10 |
| Immunogen | Fusion protein amino acids 1–1881 (full-length) of human Ankyrin-R |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932186 |
Additional Formats
Product Specific Information
- A 1:100 dilution of MA5-45732 detects Ankyrin R (~200 kDa) in 20 µg mouse brain lysate by ECL immunoblot using Goat anti-mouse IgG:HRP as secondary antibody.
- Does not cross-react with Ankyrin-B or Ankyrin-G.
- Formerly sold as clone S388A-10.
Target Information
Ankyrins are a family of proteins that link integral membrane proteins to the spectrin-actin cytoskeleton. They are involved in cell motility, activation, proliferation, contact, and maintenance of specialized membrane domains.
Ankyrin 1, the prototype of this family, was first discovered in erythrocytes and later found in brain and muscles. Mutations in erythrocytic Ankyrin 1 are associated with hereditary spherocytosis.
Multiple isoforms arise from complex alternative splicing and tissue-specific expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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