Thermo Fisher Scientific POLE3 Polyclonal Antibody
Thermo Fisher Scientific의 POLE3 폴리클로날 항체로, Western blot과 Immunocytochemistry에 적합합니다. 인간 및 생쥐 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 고순도(>95%) 항체로 연구용으로만 사용됩니다.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: -
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
- Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human POLE3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720674 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as confirmed by SDS-PAGE.
Target Information
Mitochondrial creatine kinase (MtCK) is responsible for transferring high-energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family and exists as two isoenzymes: sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes.
MtCK occurs in two oligomeric forms—dimers and octamers—unlike cytosolic creatine kinase, which is exclusively dimeric. Sarcomeric MtCK shares 80% homology with the coding exons of ubiquitous MtCK. This gene includes motifs common among nuclear genes encoding mitochondrial proteins, potentially essential for coordinated activation during mitochondrial biogenesis. Three transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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