Thermo Fisher Scientific Human TNFRSF14 Synthetic Peptide
Human TNFRSF14 유래 15개 아미노산 서열의 합성 펩타이드로, 항체 PA5-20237의 블로킹 펩타이드로 사용 가능. HSV 진입 및 면역 반응 신호전달 연구에 적합. 액상 형태, PBS 버퍼에 0.1% BSA 포함, -20°C 보관.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the amino terminus of human TNFRSF14.
PEP-0356 can be used as a blocking peptide with polyclonal antibody PA5-20237.
Target Information
TNFRSF14 is a member of the TNF-receptor superfamily. It has been identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to TNFRSF14 is part of the viral entry mechanism.
The cytoplasmic region of TNFRSF14 binds to several TRAF family members, mediating signal transduction pathways that activate immune responses. Activation of TNFRSF14 in T cells stimulates proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity.
These proteins may be useful as potential targets for controlling cellular immune responses. Multiple alternatively spliced transcript variants have been described, though the full-length nature of some variants remains undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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