Thermo Fisher Scientific TGF beta Receptor III Polyclonal Antibody
TGF beta Receptor III 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot 및 IHC(P)에서 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공. 세포막 단백질 검출에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (KA KMN GTH FVL ESP LN) corresponding to the C-terminus of human TGFbR3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: NIH 3T3 cell lysates
- Cellular location: Cell membrane
Target Information
This gene encodes the transforming growth factor (TGF)-beta type III receptor, a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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