Thermo Fisher Scientific TRPV2 Polyclonal Antibody
TRPV2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Frozen) 응용에 적합하며, 인간과 랫트 반응성. 합성 펩타이드 면역원으로 제작되어 높은 특이성과 안정성을 제공.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 0.5–1 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues C-K(744) N S A S E E D H L P L Q V L Q S P(761) of rat VRL-1 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2256574 |
Product Specific Information
Reconstitute in 50 µL of sterile water. Centrifuge to remove any insoluble material. After reconstitution, keep aliquots at -20°C for higher stability, and at 4°C with an appropriate antibacterial agent.
Target Information
VLR-1 (TRPV2) is a calcium-permeable, non-selective cation channel with outward rectification, regulated by growth factors such as IGF1, PDGF, and morphogenetic neuropeptides. It is activated by high temperatures (~52°C) rather than capsaicin or acid. Expressed mainly in medium- to large-diameter sensory neurons, VRL-1 may mediate high-threshold heat responses. Expression extends beyond sensory tissues, suggesting activation by other stimuli. VRL-1 is part of the TRPV family of vanilloid-like TRP channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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