Thermo Fisher Scientific EEA1 Polyclonal Antibody
Early endosome 항원 EEA1에 특이적인 Rabbit Polyclonal Antibody로, IHC 및 IHC(Paraffin) 적용 가능. 인간 및 유인원 종에 반응하며, 액상 형태로 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 100 and 150 of human early endosome antigen 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon, Crab-eating macaque, and White-tufted-ear marmoset
Target Information
Early endosomal antigen 1 (EEA1) is a 162 kDa membrane-bound protein specific to the early endosome and essential for fusion between early endocytic vesicles.
Early endosomes fuse with endocytic vesicles to redistribute extracellular compounds.
EEA1 contains zinc-finger-like domains at both termini, similar to those in nucleic acid binding proteins.
The carboxyl-terminal zinc-finger-like domain is conserved and critical for intracellular localization of EEA1.
Membrane association of EEA1 depends on phosphatidyl 3-kinase activity; inhibitors cause EEA1 to dissociate from early endosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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