Thermo Fisher Scientific Notch2 Polyclonal Antibody
Rabbit polyclonal antibody against human NOTCH2 protein. Suitable for IHC and IHC (Paraffin) applications. Antigen affinity purified, supplied as a liquid at 0.25 mg/mL. Predicted to cross-react with several primate species. For research use only.
- 카탈로그번호
- IHC00539x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Notch2 Polyclonal Antibody
Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 2421 and 2471 of human neurogenic locus notch homolog protein 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Monkey, Gorilla, Red-chested mustached tamarin, Northern white-cheeked gibbon, Kloss’s gibbon, and Crab-eating macaque
Target Information
Neurogenic locus notch homolog protein 2 (NOTCH2) is a highly conserved protein involved in the Notch signaling pathway. It is a type I transmembrane receptor with an extracellular domain containing multiple EGF-like repeats and an intracellular domain with various domain types.
NOTCH2 functions as a receptor for membrane-bound ligands such as Jagged1, Jagged2, and Delta1 to regulate cell-fate determination.
Defects in NOTCH2 cause Alagille syndrome type 2 (ALGS2), an autosomal dominant multisystem disorder characterized by hepatic bile duct paucity, cholestasis, and associated cardiac, skeletal, and ophthalmologic abnormalities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.