Thermo Fisher Scientific Phospho-CaMKI (Thr177) Polyclonal Antibody
CaMK1의 Thr177 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 사용 가능. 다양한 종에서 검증되었으며 1 mg/mL 액상 형태로 제공. 세포 신호전달 및 신경계 발달 연구에 적합. -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 4 publications |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | – |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Mouse, Rhesus monkey |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human CaMK1-alpha around the phosphorylation site of Thr177 (L-S-TP-A-C) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2555035 |
Target Information
CAMK1 (CaMK1) is a serine/threonine kinase belonging to the calcium/calmodulin-dependent protein kinase family. It plays key roles in cell differentiation, nervous system development, and signal transduction. CAMK1 is expressed in many tissues and functions as part of a calmodulin-dependent kinase cascade. Calcium/calmodulin directly activates CaMK1 by binding to the enzyme and indirectly promotes its phosphorylation and synergistic activation by CaMKK (CaMKI kinase).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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