Thermo Fisher Scientific Phospho-BAD (Ser134) Polyclonal Antibody
Phospho-BAD (Ser134) 폴리클로날 항체로, 세포 사멸 조절 연구용. Western blot, IHC, ICC/IF에 적합. Rabbit IgG 호스트, 비결합형 액상 포맷. -20°C 보관, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human BAD around the phosphorylation site of Ser134 (P-K-SP-A-G) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555028 |
Target Information
The protein encoded by BAD is a member of the BCL-2 family, known to regulate programmed cell death. This protein promotes apoptosis by forming heterodimers with BCL-xL and BCL-2, reversing their anti-apoptotic function. Its proapoptotic activity is controlled through phosphorylation, involving kinases such as AKT and MAP kinase, and the phosphatase calcineurin. Alternative splicing results in two transcript variants encoding the same isoform.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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