Thermo Fisher Scientific NFATC1 Recombinant Rabbit Monoclonal Antibody (ARC0076)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC0076

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 844-943 of human NFAT2 (O95644) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NFATC1,uniProtId:O95644-1,ncbiNodeId:9606,antigenRange:844-943,antigenLength:943,antigenImageFileName:MA5-35314_NFATC1_O95644-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35314_NFATC1_O95644-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849216

Product Specific Information

Immunogen sequence: PSSPSPPLPP ATQEPTCLQP CSPACPPATG RPQHLPSTVR RDESPTAGPR LLPEVHEDGS PNLAPIPVTV KREPEELDQL YLDDVNEIIR NDLSSTSTHS

Target Information

The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.