Thermo Fisher Scientific CD64 Chimeric Recombinant Human Monoclonal Antibody (H22)
인간 CD64에 특이적인 키메릭 재조합 단일클론 항체로, Flow Cytometry, ELISA, Cytotoxicity, Competition Assay 등 다양한 면역 분석에 사용 가능. HEK293 세포에서 발현된 IgG1, kappa 형 항체이며, Protein A로 정제된 액상 형태. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific CD64 Chimeric Recombinant Human Monoclonal Antibody (H22)
Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA (ELISA) | Assay-dependent |
| Cytotoxicity Assay (CT) | Assay-dependent |
| Competition Assay (CA) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | H22 |
| Immunogen | Recombinant antibody prepared by cloning the single chain fragment (scFv) derived from the murine anti-human CD64 mAb m22 into pBM1.1, fused to a deletion mutant of Pseudomonas exotoxin A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3074498 |
Product Specific Information
Specificity: This immunotoxin is specific for human CD64, targeting an epitope outside the Fc binding domain. The VH/VL antibody format retains binding activity after fusion of the m22(scFv) coding regions to the truncated ETA coding sequences.
Target Information
CD64 (FCGR1A) encodes a high-affinity Fc-gamma receptor involved in immune response. It is one of three related gene family members on chromosome 1. Dysfunction of CD64 has been associated with cervical adenitis and tetrasomy 21.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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