Thermo Fisher Scientific Felvizumab Recombinant Human Monoclonal Antibody (RSHZ19 (Felvizumab))
RSV F 단백질에 특이적인 인간화 단클론 항체로, HEK293 세포에서 발현된 재조합 IgG1 형태입니다. ELISA 및 기능적 분석에 사용 가능하며, 단백질 A로 정제된 액상 시약입니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
ELISA (ELISA)
- Tested Dilution: Assay-dependent
Functional Assay (Functional)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Human / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RSHZ19 (Felvizumab) |
| Immunogen | Prepared by humanization of an F protein-specific murine MAb, RSV19. Complementarity determining regions from murine RSV19 were inserted into a human IgG1 heavy and k light chain-variable domain framework. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074496 |
Product Specific Information
- Specificity: This antibody is specific for an epitope located between amino acids 417–432 of the conserved fusion (F) protein of RSV.
Target Information
Felvizumab is a biosimilar that targets RSV (Human respiratory syncytial virus).
RSV is a member of the Paramyxoviridae family, subfamily Pneumovirinae, and causes common respiratory tract infections such as measles and mumps.
Its genome consists of single-stranded, negative-sense RNA encoding three envelope glycoproteins:
- SH (small hydrophobic) protein of unknown function
- G (major glycoprotein, attachment protein)
- F (fusion) protein
The F proteins on the virus surface cause fusion of nearby cell membranes, forming syncytia.
While RSV typically produces mild symptoms in adults, it is a leading cause of lower respiratory tract infections and hospital visits during infancy and childhood.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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