Thermo Fisher Scientific CD64 Chimeric Recombinant Rabbit Monoclonal Antibody (H22)
인간 CD64에 특이적인 키메릭 재조합 토끼 단클론 항체로, 세포면역형광, 유세포분석, ELISA 등 다양한 면역분석에 사용 가능. HEK293 세포에서 발현된 비결합형 항체로 높은 순도와 안정성을 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | Assay-dependent |
| Cytotoxicity Assay (CT) | Assay-dependent |
| Competition Assay (CA) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | H22 |
| Immunogen | Recombinant antibody prepared by cloning the single chain fragment (scFv) derived from murine anti-human CD64 mAb m22 into pBM1.1, fused to a deletion mutant of Pseudomonas exotoxin A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3074499 |
Product Specific Information
Specificity: This immunotoxin is specific for human CD64, targeting an epitope outside the Fc binding domain. The VH/VL antibody format retains binding activity even after fusion of m22(scFv) coding regions to truncated ETA sequences.
Target Information
CD64 (FCGR1A) encodes a high-affinity Fc-gamma receptor involved in immune response. It is one of three related gene family members on chromosome 1. Dysfunction of CD64 has been studied in cervical adenitis and tetrasomy 21.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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