Thermo Fisher Scientific KCNT2 Monoclonal Antibody (S11-33)
KCNT2 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체. Western blot, IHC, ICC/IF에 사용 가능. 마우스 IgG1 형식의 비결합 항체로 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Detail |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S11-33 |
| Immunogen | Fusion protein amino acids 564–624 of mouse Slo2.1 (Slick) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735248 |
Target Information
Kcnt2 calcium (Ca2+)-activated potassium channels (KCa) are a group of 6/7-transmembrane ion channels that selectively transport K⁺ ions across biological membranes. KCa channels are broadly classified into three subtypes: SK, IK, and BK channels (small, intermediate, and big conductance).
Kcnt2 is an outward rectifying potassium channel that produces rapidly activating outward rectifier K⁺ currents. It is activated by high intracellular sodium and chloride levels and inhibited by ATP as well as inhalation anesthetics such as isoflurane. Functionally, Kcnt2 activity is suppressed upon stimulation of G-protein coupled receptors such as CHRM1 and GRIA1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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