Thermo Fisher Scientific POLR2C Recombinant Rabbit Monoclonal Antibody (3T8K8)
POLR2C 단백질을 인식하는 토끼 단클론 항체로, Western blot, IHC, ELISA에 적합합니다. 인간, 생쥐, 랫드 시료에 반응하며, HEK293 발현 시스템에서 생산된 재조합 항체입니다. 고순도의 Affinity Chromatography 정제 및 안정적인 PBS/glycerol buffer 보존.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 3T8K8 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human RPB3/POLR2C (P19387). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.37 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912081 |
Product Specific Information
- Positive test controls: 293T, Mouse kidney, Rat lung, Rat brain, Rat spleen
- Immunogen sequence:
MPYANQPTVR ITELTDENVK FIIENTDLAV ANSIRRVFIA EVPIIAIDWV QIDANSSVLH DEFIAHRLGL IPLISDDIVD KLQYSRDCTC EEFCPECSVE
Target Information
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.
Pol II is the central component of the basal RNA polymerase II transcription machinery.
It is composed of mobile elements that move relative to each other.
RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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