Thermo Fisher Scientific CD3d Recombinant Rabbit Monoclonal Antibody (2R1O10)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:200-1:800

-

Flow Cytometry (Flow)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

2R1O10

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 72-171 of human CD3D (P04234). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD3d,uniProtId:P04234-1,ncbiNodeId:9606,antigenRange:72-171,antigenLength:171,antigenImageFileName:MA5-42943_CD3d_P04234-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42943_CD3d_P04234-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.51 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2912084

Product Specific Information

Positive test controls include: Jurkat. The target is usually found in the following locations: Membrane, Single-pass type I membrane protein.

Immunogen sequence: RCNGTDIYKD KESTVQVHYR MCQSCVELDP ATVAGIIVTD VIATLLLALG VFCFAGHETG RLSGAADTQA LLRNDQVYQP LRDRDDAQYS HLGGNWARNK

Target Information

CD3d is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The CD3d protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in the CD3d gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms of CD3d have been found. Other variants of CD3d may also exist, but the full-length nature of their transcripts have yet to be defined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.