Thermo Fisher Scientific CHST1 Polyclonal Antibody
CHST1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 최적화되어 있습니다. Human, Mouse, Rat 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 1 mg/mL 농도, PBS/glycerol buffer, 4°C 단기 보관 권장.
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Applications
Western Blot (WB)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 126–171 of human CHST1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553824 |
Product Specific Information
- Detects endogenous CHST1 protein at ~47 kDa.
- Purity >95% by SDS-PAGE.
Target Information
Carbohydrate sulfotransferase 1 (CHST1), also known as KSGal6ST or KSST, is a keratan sulfate sulfotransferase. It is predominantly expressed in brain and skeletal muscle and localizes to the trans-Golgi network. CHST1 mediates the sulfation of keratan in the cornea, essential for maintaining corneal transparency. It catalyzes the transfer of sulfate groups from 3'-phosphoadenosine 5'-phosphosulfate to position six of internal or terminal galactose residues on growing keratan sulfate chains, contributing to the generation of L-selectin ligands. Mutations in CHST1 may be associated with macular corneal dystrophy (MCD).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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