Thermo Fisher Scientific PIGF Polyclonal Antibody
Thermo Fisher Scientific의 PIGF Polyclonal Antibody는 인간 PIGF 단백질을 인식하는 토끼 유래 IgG 항체로, Western blot 및 IHC에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, 고순도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1.0 µg/mL |
| Immunohistochemistry (IHC) | 1:100 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of human PIGF |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688592 |
Product Specific Information
This target displays homology in the following species:
Cow: 86%; Dog: 93%; Horse: 92%; Human: 100%; Mouse: 86%; Pig: 86%; Rat: 86%; Sheep: 86%
Target Information
Phosphatidylinositol-glycans (PIGs) are multi-pass transmembrane proteins localized to the endoplasmic reticulum. PIGs are essential for the biosynthesis of the glycosylphosphatidylinositol (GPI) anchor. Some PIG proteins are components of the GPI transamidase complex and play roles in recognizing the GPI attachment signal or the lipid portion of GPI. Others belong to the glycosyltransferase complex and function in transferring N-acetylglucosamine (GlcNAc) to phosphatidylinositol (PI).
PIG-F functions as an auxiliary subunit of ethanolamine phosphate (EtNP) transferases, associating with PIG-O to ensure its expression and stability. Together, these proteins catalyze the transfer of EtNP to the third mannose (Man-3) of GPI. Mutations in the PIG-F gene may block EtNP addition to Man-3, leading to the absence of GPI-anchored proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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