Thermo Fisher Scientific DUSP11 Polyclonal Antibody
Thermo Fisher Scientific의 DUSP11 폴리클로날 항체는 Mouse DUSP11 단백질을 인식하는 Rabbit IgG 형 항체입니다. Western blot에 최적화되어 있으며, 액상 형태로 제공됩니다. 0.5 mg/mL 농도, PBS + 2% sucrose 버퍼에 보관되며, -20°C에서 보존 가능합니다.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested Dilution – 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of mouse DUSP11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691177 |
Product Specific Information
This target displays homology in the following species:
Cow: 86%; Dog: 86%; Horse: 79%; Human: 100%; Mouse: 79%; Pig: 86%; Rabbit: 86%; Rat: 79%
Target Information
DUSP11 (dual specificity phosphatase 11, RNA/RNP complex 1-interacting) is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation.
Different members of the dual specificity phosphatases family show distinct substrate specificities for various MAP kinases, tissue distribution, subcellular localization, and inducibility of expression by extracellular stimuli.
DUSP11 is localized to the nucleus and binds directly to RNA and splicing factors, suggesting a role in nuclear mRNA metabolism.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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