Thermo Fisher Scientific SHP2 Monoclonal Antibody (5F2)
SHP2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB, ICC/IF, IP 등에 사용 가능. A431 세포를 양성 대조군으로 권장. 세포 성장, 분화, 신호전달 연구용으로 적합. 연구용 전용 제품.
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Thermo Fisher Scientific SHP2 Monoclonal Antibody (5F2)
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | - |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
| Immunoprecipitation (IP) | 1 µL | - |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5F2 |
| Immunogen | Recombinant human GST-SHP2 protein purified from E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_1960640 |
Product Specific Information
A suggested positive control for this product is A431 cells.
Target Information
The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family, known to regulate various cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP contains two tandem Src homology-2 domains that mediate interaction with substrates and is widely expressed in most tissues.
It plays a regulatory role in cell signaling events related to mitogenic activation, metabolic control, transcription regulation, and cell migration.
Mutations in this gene are associated with Noonan syndrome and acute myeloid leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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