
Thermo Fisher Scientific Complement C4 Monoclonal Antibody (49H9)
Human plasma에서 정제된 단백질을 면역원으로 한 Mouse IgG2b 단클론 항체. Western blot, ELISA, Immunoprecipitation에 사용 가능. Complement C4 단백질 검출에 적합하며 연구용으로만 사용.
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Thermo Fisher Scientific Complement C4 Monoclonal Antibody (49H9)
Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| ELISA (ELISA) | Assay-dependent |
| Immunoprecipitation (IP) | 1 µL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 49H9 |
| Immunogen | Protein purified from Human plasma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_1955586 |
Product Specific Information
A suggested positive control for this product is human plasma.
Target Information
This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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