Thermo Fisher Scientific A1BG Monoclonal Antibody (54B12)

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Immunoprecipitation (IP)

2 µg

-

Product Specifications

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

54B12

Immunogen

Protein purified from Human plasma

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2289039

Product Specific Information

A suggested positive control for this product is human plasma.

Target Information

Alpha-1-B glycoprotein (A1BG) which is a plasma protein with no known function belongs to the immunoglobulin superfamily. Although the human A1BG has been known for four decades, and the information about the amino acid sequence, chromosomal assignment, and even genetic polymorphism in different populations have been known, no biological function has been suggested. A1BG (Mr approximately equal to 63,000) consists of one polypeptide chain of 474 amino acids with four glucosamine oligosaccharides. The polypeptide has five intrachain disulfide bonds and consists of five repeating structural domains, each containing about 95 amino acids and one disulfide bond. Recently human cysteine-rich secretory protein 3 (CRISP-3) has been found to be a binding partner of A1B, suggesting the A1BG-CRISP-3 complex displays a protecting function from a potentially harmful effect of free CRISP-3 in circulation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.