Thermo Fisher Scientific CD275 (B7-H2) Polyclonal Antibody
CD275 (B7-H2) 단백질을 표적으로 하는 Thermo Fisher Scientific의 산양 유래 폴리클로날 항체. Western blot 및 유세포분석에 적합하며, 인간 시료 반응성. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 순도를 제공. 연구용으로만 사용 가능.
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- PA547177
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Applications
Western Blot (WB)
- Tested Dilution: 2 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 0.25 µg per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human B7-H2 (Asp19–Ser258) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2610087 |
Product Specific Information
- In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant mouse B7-H2 and recombinant human B7-H1 is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and peripheral tissue cells that binds to the inducible co-stimulator receptor (ICOS).
ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function.
ICOSL is expressed on monocytes, dendritic cells, and B cells, and can be induced by inflammatory stimuli in peripheral tissue.
Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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