Thermo Fisher Scientific KREMEN1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Immunohistochemistry (IHC)

5-15 µg/mL

-

Flow Cytometry (Flow)

2.5 µg per million cells

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Kremen-1 Ala20-Gly395 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:KREMEN1,uniProtId:Q99N43-1,ncbiNodeId:10090,antigenRange:20-395,antigenLength:473,antigenImageFileName:PA5-47176_KREMEN1_Q99N43-1_Goat.svg,antigenImageFileNamePDP:PA5-47176_KREMEN1_Q99N43-1_Goat_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2605804

Product Specific Information

In direct ELISAs, approximately 15% cross-reactivity with recombinant human Kremen-2 and recombinant mouse Kremen-2 is observed.

Reconstitute at 0.2 mg/mL in sterile PBS.

Target Information

KREMEN1 is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. This protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.