Thermo Fisher Scientific p75NTR Polyclonal Antibody
Thermo Fisher Scientific의 p75NTR Polyclonal Antibody는 인간, 마우스, 랫트 반응성을 가지며 WB 및 IHC에 적합합니다. 합성 펩타이드 항원을 기반으로 제작된 Rabbit IgG 항체로, 신경 성장 인자 수용체 연구에 유용합니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific p75NTR Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 10–50 µg/mL | - |
| Immunohistochemistry (IHC) | 10–50 µg/mL | - |
| Miscellaneous PubMed (Misc) | - | View 4 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the extracellular domain of human p75NTR (low affinity NGF receptor, p75, LNGFR, p75NTR) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
- The antigen is homologous in many other species including mouse and rat.
- Specificity of this antibody: p75NTR
Target Information
Neurotrophic factors control the survival, differentiation, and maintenance of neurons in the peripheral and central nervous systems, and of other neural crest-derived cell types. Developing sympathetic neurons are dependent upon nerve growth factor (NGF) during target competition in vivo.
Antibodies reacting specifically with NGFR p75 are useful tools in the detection and characterization of NGFR p75, enhancing understanding of development, plasticity, and repair mechanisms in the nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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