
Thermo Fisher Scientific IL-6 (Interleukin-6)/Interferon beta-2 (Hybridoma Growth Factor) Monoclonal Antibody (IL6/4642)
인간 IL-6 단백질을 인식하는 Mouse monoclonal 항체. IHC(P) 및 Peptide Array에 사용 가능. 염증 및 면역 반응 연구에 적합. Protein A/G 정제, PBS + 0.05% BSA 용액 형태. 4°C 보관, 연구용 전용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IL6/4642 |
| Immunogen | Recombinant fragment (around aa1–200) of human IL-6 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Human heart or adrenal gland; stimulated peritoneal macrophages
- Cellular Location: Cytoplasm, Extracellular (Secreted)
Target Information
IL-6 encodes a cytokine involved in inflammation and B cell maturation. It acts as an endogenous pyrogen, inducing fever in autoimmune diseases or infections. IL-6 is primarily expressed at sites of acute and chronic inflammation, secreted into serum, and activates transcriptional inflammatory responses via the IL-6 receptor alpha.
Elevated IL-6 levels are associated with diseases such as diabetes mellitus, systemic juvenile rheumatoid arthritis, Kaposi sarcoma, and COVID-19 (SARS-CoV-2 infection).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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