Thermo Fisher Scientific TRPM5 Polyclonal Antibody
Rabbit polyclonal antibody specific for Human TRPM5 recombinant protein. Unconjugated, liquid form, suitable for research use only. Plays a role in taste transduction and calcium-activated ion channel studies. Stable at 4°C short term or -20°C for long...
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Thermo Fisher Scientific TRPM5 Polyclonal Antibody
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human TRPM5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856556 |
Product Specific Information
Immunogen sequence:
KEAEHKREHL ERDLPDPLDQ KVVTWETVQK ENFLSKMEKR RRDSEGEVLR KTAHRVDFIA KYLGGLREQE KRIKCLESQI NYCSVLV
Target Information
This gene encodes a member of the transient receptor potential protein family, which is a diverse group of proteins with structural features typical of ion channels.
TRPM5 plays an important role in taste transduction and functions as a calcium-activated, non-selective cation channel that carries Na⁺, K⁺, and Cs⁺ ions equally well, but not Ca²⁺ ions.
It is activated by lower concentrations of intracellular calcium and inhibited by higher concentrations.
This protein is highly temperature-sensitive, showing steep increases in inward currents between 15°C and 35°C.
The gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5 and is imprinted, expressed exclusively from the paternal allele.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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