Thermo Fisher Scientific extracellular MC2R Polyclonal Antibody
Rabbit polyclonal antibody targeting human MC2R extracellular domain. Validated for WB and IHC applications. Lyophilized form, reconstitutable in MQ water. Suitable for research use only, not for diagnostic procedures.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 60–110 of extracellular domain of human MC2R conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of MQ water. Centrifuge to remove any insoluble material.
- The peptide shares 85% identity with mouse sequence.
- Specificity: MC2R.
Target Information
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins are peptides derived from pro-opiomelanocortin. MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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