Thermo Fisher Scientific RAD1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

2-5 µg/mL

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues 133-148 of human Rad1.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2176292

Product Specific Information

Human Rad1 is a homolog of Schizosaccharomyces pombe Rad1.

Suggested positive control: Hela whole cell lysate, 293 whole cell lysate, 293, HeLa, or NIH-3T3, 3T3 whole cell lysate.

Target Information

Rad1 is a component of a heterotrimeric PCNA-like complex that contains Rad9 and Hus1 proteins. This complex is involved in the 9-1-1 cell cycle checkpoing response complex that plays a major role in DNA repair, by associating with Rad17 and several components of the PCNA-loading heteropentamer replication factor C. Mutants has been shown to partially restore radiation resistance and G2-checkpoint activity. It has also been shown to possess exonuclease activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.