Thermo Fisher Scientific LOXL2 Recombinant Rabbit Monoclonal Antibody (7H25L21)
인간 LOXL2 단백질을 인식하는 재조합 토끼 모노클로날 항체. Western blot 및 Immunocytochemistry에 적합. 높은 특이성과 재현성을 제공하며, 동물 유래 성분이 없는 포뮬레이션. 단기 4°C, 장기 -20°C 보관 권장.
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- 702694
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Applications
Western Blot (WB)
- Tested Dilution: 2.5 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 5 µg/mL
- Publications: 1 publication available
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7H25L21 |
| Immunogen | Peptides corresponding to human LOXL2 (aa28–aa45, aa239–aa258) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2716885 |
Product Specific Information
This antibody is predicted to react with Monkey, Bovine, and Cat.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, followed by screening and selection of optimal clones for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
The LOXL2 gene encodes a member of the lysyl oxidase family, essential for connective tissue biogenesis. It produces an extracellular copper-dependent amine oxidase that catalyzes crosslink formation in collagens and elastin.
The conserved C-terminal sequence confers amine oxidase activity, while the variable N-terminal region may contribute to roles in developmental regulation, senescence, tumor suppression, cell growth, and chemotaxis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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