Thermo Fisher Scientific UBE2B Polyclonal Antibody
UBE2B 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 면역세포화학에 적합합니다. 인간 및 마우스 반응성이 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 DNA 손상 복구 연구에 활용됩니다.
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- PA521316
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:10,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment containing a sequence corresponding to amino acids 1–182 of UBE2B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.72 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11154359 |
Product Specific Information
- Recommended positive controls: mouse brain, 3xFlag-human UBE2B-transfected 293T
- Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (95%), Xenopus laevis (98%), Pig (100%), Rabbit (100%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation.
Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s).
UBE2B is a member of the E2 ubiquitin-conjugating enzyme family and is required for post-replicative DNA damage repair.
Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, indicating high conservation in eukaryotic evolution.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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