Thermo Fisher Scientific HRH3 Polyclonal Antibody
Rabbit polyclonal antibody against Histamine H3 Receptor (HRH3). Validated for Western blot applications with high specificity. Suitable for use with HeLa and Raji cell lysates. Supplied as a liquid, 1 mg/mL concentration, stored at 4°C or -20°C. For r...
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 299–389 of Histamine H3 Receptor (Uniprot ID: Q9Y5N1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11152054 |
Product Specific Information
- Recommended positive controls: HeLa, Raji
- Predicted reactivity: Rhesus Monkey (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
H3 Histamine Receptor regulates the release of neurotransmitters such as norepinephrine and somatostatin.
In histamine-containing neurons of the brain, the H3 receptor acts as a presynaptic autoreceptor, while in nonhistamine-containing neurons (both central and peripheral nervous systems), it acts as a presynaptic heteroreceptor.
Multiple isoforms of H3 receptors are produced by alternative splicing.
Histamine H3 receptor has been reported primarily in the brain. ESTs have been isolated from brain (normal and cancer), breast cancer, colon cancer, and retinoblastoma libraries.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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