Thermo Fisher Scientific KLF4 Monoclonal Antibody (1E6)
인간 KLF4 단백질을 검출하는 Mouse IgG1 단클론 항체. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. 비결합형 액상 형태로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관 가능. 연구용으로만 사용.
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Thermo Fisher Scientific KLF4 Monoclonal Antibody (1E6)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 | 1 publication |
| ELISA | 1:10,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1E6 |
| Immunogen | Purified recombinant fragment of human KLF4 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10980668 |
Product Specific Information
MA5-15695 targets KLF4 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human KLF4 expressed in E. coli.
MA5-15695 detects KLF4 with a predicted molecular weight of approximately 54 kDa.
Target Information
Kruppel like factor 4 (KLF4) is encoded by the KLF4 gene located on chromosome 9 in humans. Also known as gut-enriched Kruppel-like factor (GKLF) or epithelial zinc-finger protein (EZF), it belongs to the family of conserved Kruppel-like factor DNA-binding zinc finger transcription factors.
KLF4 plays a crucial role in cellular processes such as endothelial signaling, adipogenesis, differentiation, embryogenesis, and cell cycle control.
As one of the four Yamanaka factors, it is essential for reprogramming differentiated cells into pluripotent stem cells.
Its localization determines biological function — nuclear localization is associated with oncogenic activity, while cytosolic localization is linked to tumor suppression.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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