Thermo Fisher Scientific GFI1 Monoclonal Antibody (5D7)
상품 옵션 정보 | ||||||||
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
MA515688 | - | Thermo Fisher Scientific MA515688 GFI1 Monoclonal Antibody (5D7) 100 ul pk | 재고문의 | pk | 680,000원 | - | 748,000원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1:500-1:2,000
ELISA (ELISA)
1:10,000
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse / IgG1
Class
Monoclonal
Type
Antibody
Clone
5D7
Immunogen
Purified recombinant fragment of human GFI1 expressed in E. Coli.
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.03% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_10980909
Product Specific Information
MA5-15688 targets GFI1 in indirect ELISA, WB applications and shows reactivity with Human samples.
The MA5-15688 immunogen is purified recombinant fragment of human GFI1 expressed in E. Coli.
MA5-15688 detects GFI1 which has a predicted molecular weight of approximately 45kDa.
Target Information
GFI1 is a nuclear zinc finger (ZF) transcriptional repressor that plays an important role in hematopoiesis and inner ear development, and has been implicated in lymphomagenesis. The Gfi1 protein expression is regulated by the ubiquitin-proteasome system. It is reported that ubiquitin ligase Triad1 interacts with the DNA-binding domain of Gfi-1. Gfi-1 represses transcription by directly binding to the consensus DNA sequence in the promoters of its target genes. Deficiency of Gfi-1 causes neutropenia and an accumulation of granulomonocytic precursor cells that is reminiscent of a myelodysplastic syndrome in mice.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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