Thermo Fisher Scientific ALDH1A1 Monoclonal Antibody (5A11)
ALDH1A1 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC/IF, ELISA에 적합합니다. 인간 시료에 반응하며 약 55kDa 단백질을 검출합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 5 µg |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5A11 |
| Immunogen | Purified recombinant fragment of human ALDH1A1 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11009627 |
Product Specific Information
MA5-15692 targets ALDH1A1 in indirect ELISA, IHC, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human ALDH1A1 expressed in E. coli.
MA5-15692 detects ALDH1A1, which has a predicted molecular weight of approximately 55 kDa.
Target Information
ALDH1A1 belongs to the aldehyde dehydrogenase family of proteins. This enzyme participates in the major oxidative pathway of alcohol metabolism.
Two major liver isoforms—cytosolic and mitochondrial—can be distinguished by electrophoretic mobility, kinetic properties, and subcellular localization.
Most Caucasians have both isozymes, while about 50% of Orientals possess only the cytosolic isozyme, lacking the mitochondrial form. This absence may correlate with a higher frequency of acute alcohol intoxication among Orientals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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