
Thermo Fisher Scientific PHKB Polyclonal Antibody
PHKB 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IP에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 인간 PHKB에 반응. 연구용으로만 사용, 4°C 보관.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 650–700 of human Phosphorylase b kinase regulatory subunit beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rabbit
Target Information
Phosphorylase kinase is a hexadecameric enzyme composed of four copies of four subunits encoded by PHKA, PHKB, PHKG, and PHKD. This serine/threonine-specific kinase converts glycogen phosphorylase b to glycogen phosphorylase a, releasing glucose-1-phosphate from glycogen.
PHKB (Phosphorylase b kinase regulatory subunit beta) is a 1093 amino acid subunit with regulatory functions controlled by phosphorylation. Defects in PHKB cause glycogen storage disease type 9B, characterized by mild hepatomegaly and slightly elevated transaminase and plasma lipids, with gradual improvement with age.
Four isoforms of PHKB are produced by alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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