
Thermo Fisher Scientific ALK Monoclonal Antibody (OTI2B3), TrueMAB
인간 ALK 단백질(aa1300-1620)에 특이적인 Mouse IgG2a 단클론 항체로, Western blot에 적합합니다. TrueMAB 형식으로 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 -20°C에서 안정적으로 보관 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1300–1620 of human ALK produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Anaplastic Lymphoma Receptor Tyrosine Kinase (ALK) belongs to the insulin receptor superfamily and plays a vital role in brain development. Mutations, rearrangements, and amplifications of the ALK gene are associated with tumors such as anaplastic large cell lymphoma, neuroblastoma, and non-small cell lung cancer. Chromosomal rearrangement often results in a fusion gene between ALK and nucleophosmin (NPM), producing an oncogenic NPM-ALK fusion protein. ALK is a receptor protein-tyrosine kinase with transmembrane and extracellular domains, exhibiting high sequence similarity to LTK.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: TA801294_ALK_Q9UM73-1_House_mouse.svg / TA801294_ALK_Q9UM73-1_House_mouse_PDP.jpeg)
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