Thermo Fisher Scientific beta-2 Adrenergic Receptor Polyclonal Antibody
Human beta-2 Adrenergic Receptor를 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 고순도 제품(>95%)이며, 47/68/95 kDa 밴드 검출. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 351–400 of Human AR-beta2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2803261 |
Product Specific Information
- Multiple bands observed at 47 kDa, 68 kDa (glycosylated), and 95 kDa (dimer)
- Purity >95% by SDS-PAGE
Target Information
Adrenergic receptors (ARs) are members of the 7-transmembrane domain G-protein-coupled receptor superfamily that bind the endogenous catecholamines epinephrine and norepinephrine.
Pharmacological, structural, and molecular cloning data indicate significant heterogeneity within this receptor family.
Nine receptor subtypes have been identified thus far including:
- Three alpha-1 AR subtypes (1A/D, 1B, and 1C)
- Three alpha-2 ARs (2A, 2B, and 2C)
- Three beta AR subtypes (1, 2, and 3)
ARs participate in either the onset or maintenance of several disease states including hypertension, cardiac dysfunction (congestive heart failure, ischemia, arrhythmias), diabetes, glaucoma, depression, and impotence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-86483_beta-2_Adrenergic_Receptor_P07550-1_Rabbit.svg
- PA5-86483_beta-2_Adrenergic_Receptor_P07550-1_Rabbit_PDP.jpeg
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