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Thermo Fisher Scientific PR3 Recombinant Rabbit Monoclonal Antibody (3I3M1)
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Thermo Fisher Scientific PR3 Recombinant Rabbit Monoclonal Antibody (3I3M1)

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PR3 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. 인간 및 마우스 반응성. ICC/IF 및 ELISA에 적합. 고순도 친화 크로마토그래피 정제, 안정적 액상 형태로 -20°C 보관.

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마지막 업데이트 2025. 08. 05. 오전 06:13
Thermo Fisher Scientific MA542734 PR3 Recombinant Rabbit Monoclonal Antibody (3I3M1) 100 ul pk판매 단위 pk ·
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714,600원VAT 포함 786,060원

Thermo Fisher Scientific · Thermo Fisher Scientific PR3 Recombinant Rabbit Monoclonal Antibody (3I3M1)

Applications and Tested Dilution

Application Tested Dilution
Immunocytochemistry (ICC/IF) 1:50–1:200
ELISA 1 µg/mL

Product Specifications

항목 내용
Species Reactivity Human, Mouse
Host / Isotype Rabbit / IgG
Expression System HEK293 cells
Class Recombinant Monoclonal
Type Antibody
Clone 3I3M1
Immunogen A synthetic peptide corresponding to amino acids 1–100 of human Proteinase 3 (PR3, UniProt P24158)
Conjugate Unconjugated
Form Liquid
Concentration 0.4 mg/mL
Purification Affinity Chromatography
Storage Buffer PBS (pH 7.3) with 0.05% BSA, 50% glycerol
Contains 0.02% sodium azide
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Ambient (domestic); Wet ice (international)
RRID AB_2911875

Product Specific Information

  • Positive test controls include: Mouse liver
  • Immunogen sequence:
    MAHRPPSPAL ASVLLALLLS GAARAAEIVG GHEAQPHSRP YMASLQMRGN PGSHFCGGTL IHPSFVLTAA HCLRDIPQRL VNVVLGAHNV RTQEPTQQHF

Target Information

Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246).
By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369).
May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279).
[UniProt]


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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