Thermo Fisher Scientific Human IgG3 Recombinant Rabbit Monoclonal Antibody (6Q4J8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

6Q4J8

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human IgG3 (P01860)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911871

Product Specific Information

Positive test controls include: human plasma.

Immunogen sequence: VHTFPAVLQS SGLYSLSSVV TVPSSSLGTQ TYTCNVNHKP SNTKVDKRVE LKTPLGDTTH TCPRCPEPKS CDTPPPCPRC PEPKSCDTPP PCPRCPEPKS C

Target Information

Human IgG3, also known as human immunoglobulin G3, is a subclass of human IgG antibodies that is produced by the immune system in response to antigens. It is the least abundant subclass of IgG in the blood and plays a minor role in defense against pathogens. IgG3 works by binding to specific antigens and promoting their clearance from the body through various mechanisms, including phagocytosis and complement activation. IgG3 is also involved in other immune responses, such as antibody-dependent cellular cytotoxicity and neutralization of toxins. Human IgG3 can be used in research to study the immune response to pathogens and to develop diagnostic tests and therapeutic interventions for infectious and autoimmune diseases.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.