Thermo Fisher Scientific NeuN Recombinant Rabbit Monoclonal Antibody (SR45-07)
NeuN 단백질을 인식하는 재조합 토끼 단클론 항체로, WB, IHC, ICC, Flow Cytometry에 사용 가능. 인간, 마우스, 랫트 반응성. HEK293 발현, Protein A 정제, 1 mg/mL 농도. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:10,000 |
| Immunocytochemistry (ICC/IF) | 1:250–1:500 |
| Flow Cytometry (Flow) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SR45-07 |
| Immunogen | Synthetic peptide within human NeuN aa 20–60 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2898845 |
Target Information
Fox-3, also known as NeuN, HRNBP3, RBFOX3 (RNA binding protein, fox-1) or Fox-1 homolog C, is a 350 amino acid protein containing one RNA recognition motif (RRM) domain. Localized to both the nucleus and cytoplasm, Fox-3 regulates alternative splicing events. The Fox-3 gene is located on human chromosome 17, which encodes over 1,200 genes and includes key tumor suppressors such as p53 and BRCA1.
- p53: Maintains genomic integrity by regulating DNA repair and apoptosis. Loss of function is linked to malignant growth and Li-Fraumeni syndrome.
- BRCA1: Involved in DNA repair and associated with early-onset breast and ovarian cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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